Biology matters.

Not many long term studies have been conducted specifically on transgender patients, but the ones that have reveal alarming results. Considering the spike in children seeking trans treatments in the past decades, more studies are urgently required.

A 20-year follow-up study of gender diverse people suggests transgender men receiving testosterone therapy were at an 11% greater risk of developing blood clots.

Led by investigators from the Department of Endocrinology and Center of Expertise on Gender Dysphoria at Vrije Universiteit Medical Center, results of the study indicate patients saw the greatest increase of hematocrit during the first year and provide insight into potential avenues for mitigating this risk.

Erythrocytosis is common in transgender men treated with testosterone, especially in those who smoke, have high body mass index (BMI) and use testosterone injections," said lead investigator Milou Cecilia Madsen, MD, of the VU University Medical Center Amsterdam in the Netherlands, in a statement.

Medicine has long understood the biological differences between males and females. Protocols are developed accordingly.

Transgender patients rely on invasive and unnatural daily drug regimes to keep up the appearance of transitioning. The consequences of such treatments are only now becoming obvious.

Binary spokeswoman, Kirralie Smith, said more studies are required.

“What are the long-term effects on teenage girls injecting or using testosterone long term? There small amount of data available is very concerning and yet experiments on children continue. Blood clots are a very serious side-effect. What other health issues will girls face as they enter their thirties, forties and beyond?”